
Yes, one of my dogs had a histocytoma on her leg, it was flat and about the size of a 5p piece (she's a Cairn, so on her leg this was not a small lump) - next to a joint.
brought her to the vet and he recommended surgery because of its location - any bigger and they would need to take out too much tissue. At that time, of course, it was not clear what it was - as your vet said it is really impossible to tell without a biopsy. Dropped her off for surgery and the vet called later in the day to say he was not going to operate because he thought the lump was smaller than he'd seen it earlier in the week. (I have a good vet!) Got some cream to put on it a couple of times a day and within 2 or 3 weeks it was gone.