About 2 years ago, one of my bitches had the two stage misalliance jab after getting 'frisky' with my then 6 month old dog (I kept them apart, but literally took my eye of them for a few seconds while I filled the kettle and they were in a tie !)

I never intended to breed from her, so she had the jabs.

At the time the vet told me it may increase her chances of Pyometria - did he mean for just that season or for all future seasons ?

(hope you don't think I was irresponsible - the boy has since been neutered)

Many thanks

Chris xx

The increased risk is overall, but m9ost likely for that season. 

In fact the risk increases with each season in a bitches life. 

Maybe it is more frequent in bitches that haven't had litters in that they have more seasons and also the hormones that have the most influence on the likelihood of pyo remain raised far longer in the unmated bitch.

Most breeders I know for this reason spay their bitches after their last litter.

Sadly some bitches can get Pyo after a first season, and I know of two last year that got it whilst in whelp (lost their litters and had to be spayed).