can anyone tell me if it's better to keep a dog or a bitch with it's mother out of the litter of the puppes

ooo yea my dog is a Staffordshire bull terrier the pups will be staffy cross irish staffy.

Somebody correct me if I am wrong, but I would say a dog. I beleive that two bitches may have more "issues" than a dog and bitch, regardless of whether it is it's offspring. :-)

But would they be alright if theu were both neutered???

I agree with Tigerlilly, a dog and a bitch usually get on better than two bitches. If you have the bitch spayed after her litter (I assume from the cross it was an accident) then you shouldn't have any problems and certainly no more pups. :-)