
As far as I am aware there is no such breed recognised as the American Mastiff, and why would anyone deliberately set out to cross breed them??? If you wnat a cross breed then go to a resuce kennel and give a dog a home, sadly there are a lot of bully crosses bred for macho reasons who then end up in rescue. Don't encourage the breeding of more.
If you like Real Mastiffs then get yourself a well bred pedigree one with back up from a knowledgeable breeder.