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By sierra
Date 09.01.02 16:02 UTC
I've been getting in all sorts of various articles to go up on the site, so it will be moving to its own domain in the near future. In the meantime, I'll try to put it up on a webspace that is accessible by all. I know some of you have indicated that you're having trouble accessing it. If you do have problems, please email me and I'll email the articles to you.
I've spent the past few days researching various inherited genetic disorders for all breeds, which is where my request for help arises. I've gotten through the cardiac disorders and am now working on the blood disorders. Hopefully, within the next week, I'll be able to put up a list of all breeds with incidences of genetic disorders noted. I'd like your help in making sure this list covers all the problem areas. If you would please, please email me with a list of noted genetic problems within your respective breeds, I'd really appreciate it.
Leigh, I haven't seen any so for for Braccos. Are there any?
Thanks so much. You guys are the ones making this endeavor possible.
By Leigh
Date 09.01.02 16:15 UTC
Bracchi, hips and Bending Bones (No technical name yet, still at the research stage).Entropian/Ectropian.
By sierra
Date 09.01.02 16:39 UTC
Thanks. They are an exceptionally healthy breed. Let's hope they continue to be that way for many, many more centuries.
By Bec
Date 09.01.02 17:23 UTC
With Parson Russell Terriers it is PLL (Primary Lens Luxation) and possibly Luxating Patella.
Bec
By westie lover
Date 09.01.02 18:48 UTC
Westies can inherit: CMO: Craniomandibular Osteoarthropathy ( phew!) and Demodetic Mange, I have heard other people mention Luxating Patella, but haven't seen it myself.
Legge Perthes is thought to be hereditary, but it is a grey area as it seems it can be brought on by over exersise too, but there is no knowing whether if exersised correctly, they may avoid it. There was a study done by Mr. Robinson many years ago; test matings were done where both parents were affected and around 50% of puppies contracted it, but it can crop up where several generations were free of it. One of them nasty ressesives I guess.
Many Westies also suffer allergy/skin problems, probably a faulty immune system, but again very hard to prove its hereditary, but it might be in some cases .
Though there is no problem recognised by the eye testing scheme, Westies are "under investigation", Junior cataracts have been known, I have had one puppy that had it long ago, but I dont think its a big problem in the breed.
There has also been a spate of Liver Shunts a few years ago, but again this could be congenital rather than hereditary, but it did seem to crop up from dogs of simaliar bloodlines.
After reading this it doesn't sound that helpful!! Sorry there are so many ifs and buts, if Irene's about she may have something more useful to add.
By Val
Date 09.01.02 19:22 UTC
Rough Collies should be tested for eye problems although experts still can't agree on the mode of inheritance. CEA - Collie Eye Anomaly & PRA. Can't say that HD is unknown, but it's not common and very few breeders test for either.
Wasn't able to make the link at all Sierra.

Border Collies are tested for CEA /Pra hipscored and now quiet often hearing tested.Gillian
By dizzy
Date 09.01.02 21:02 UTC
sharpei suffer from,fevers-[hock attacks] ,also ammolydosis. the usa along with the uk have had these looked into for years trying to find a gene for it, thousands have been spent but its stll not proven, the fevers are caused because the dog cant absorb protein ,so the protien gathers around organs and joints etc ,causing fevers ,these usually only last for a night, the dog will have swollen hocks,muzzle or other and become feverish ,possibly lame, rested up for the night it will seem like nothing happened by the next day usually, ammoloyd is where the protiens lay onto the liver as it cant be absorbed ,at around 3-4 the dog can go into liver failure and die within a day or two, this is in the breed and no-one as far as i know can garauntee not to produce either of the above, its not rampant but it is about,
By bobby70
Date 10.01.02 21:51 UTC
Stafford's have eye problems and some are now saying that they are showing HD problems but not a lot of people are testing for this yet
bobby
By sierra
Date 09.01.02 21:39 UTC
Val, email me and I'll send you all the articles and charts. For some reason some people are unable to access the site; hence, it is being moved. I've come up with quite a few genetic disorders for Collies so far and am only through the cardio, endocrine, blood and some of the eye disorders. I'm trying to decide the easiest way to put up the genetic disorder chart. Anyone with ideas of how they would like to see it? As a complete chart? By breed? By Group?

I think that the incidence of a disorder is important, and I fear impossible to obtain, so that things are kept in Proportion. I remeber reading on the back of the short eye leaflet from the BVA that the incidence of PRA in Border Collies before the Eye schem was higher than 14% and after 20 years testing is less than a 1/4 of one percent!
One would imagine that similar stats would apply to other breeds with PRA, so in a breed like mine where all breeding stock is put through the scheme the size of the problem would be similar, and the successes of limiting the problem too one would hope!
It is all to easy when pointing out the nasty's that the breeds are riddled with cases. I am only full of questions I am afraid, not the answers :(
By Bec
Date 09.01.02 22:55 UTC
I would like to see it by breed but separated into groups if that makes sense although if you are intending it for the international market it may best be done just by breed as the groups vary between countries.
Bec
By sierra
Date 09.01.02 23:58 UTC
Right now it's sitting at 178 breeds. One of the problems is that every blood disorder has a disclaimer stating that For many breeds and many disorders, the studies to determine the mode of inheritance or the frequency in the breed have not been carried out, or are inconclusive. We have listed breeds for which there is a consensus among those investigating in this field and among veterinary practitioners, that the condition is significant in this breed.
It is interesting to note that one of the blood disorders was practically eliminated in Otterhounds through diligent and careful breeding. That doesn't happen unless someone takes all those nasty things into account and tries like all get out to intelligently breed. I'm all for not putting my head in the sand and being aware, but not terrified of what may lie ahead.
I'm going to beg my husband very nicely to purchase a website for me. That way I'll be able to keep it in both formats.
I was the victim of a breeder who hid epilepsy. Her stud dog was one of the top GSPs in the breed and ironically is also featured in Maxine Collins' GSP book. I bought one of the puppies, paying a fortune at that time for him. Not only did he have juvenille cataracts (back when they were first becoming aware of juvenille cataracts in GSPs, but also had epilepsy that I learned to cope with. The breeder's response? Utter disbelief. She denied to the end of her time on earth that there were epilepsy problems in *her* dogs or in the breed for that matter.
I'm actually learning a lot through this research. The incidence rate is so hard to calculate when people hide it beneath the covers. It also makes it hard to determine how the disorder is inherited.
Back to the grindstone -- I'm actually almost through cardiovascular, endocrine, blood, and eye disorders. Skin, immune systems, gastrointestinal, reproductive, respiratory, urinary, and nervous systems to go!

Sierra, you're correct when you say that in many cases the mode of inheritance, if any, is inconclusive in so many cases. Environmental causes (including diet, lifestyle) are contributary in a great number of instances.
Thinking of Flatcoated Retrievers, we test for hips. With an average score of 9 point something there is no great problem at all, but keep a watching brief.
We also test for the usual eye problems; again, no great cause for concern. The problem with the actual gonioscopy test for glaucoma you are well aware of. The clinical incidence of the disease is low, but suspected of being hereditary.
Cancer occurs, but genetic predisposition non-proven.
Hypothyroidism occurs in a few individuals - non-proven to be hereditary in UK dogs, tho' they do think it may be in the States, I think. Of course, there is thought to be a genetic link in humans.
Jo and the Casblaidd Flatcoats
By jusjokin
Date 21.01.02 19:59 UTC
regarding the Lets talk breeding site-seen it advertised on Pedigreedogs but couldn't get on ot-any chance of the correct address please?
By dizzy
Date 21.01.02 20:35 UTC
www.dogstuff.info
By Keesy8
Date 21.01.02 20:58 UTC

Glad you put the link up saves me doing it
By sierra
Date 22.01.02 02:29 UTC
Interesting. I'll have to take a look at pedigreedogs.
Sierra I have yet to look at your website in great detail but first impressions are it's pretty damn good. Forgive me if this has been covered already but what about including the pro's and cons of having a stud dog? We see posts by people saying they wanna use their dog at stud and I am a firm believer that those providing a stud dog have just as much responsibility as those providing the bitch and rearing a litter.
Take me for example, I have an entire male and if someone were to ask me if they could use him at stud I would have to look into it just as deeply as if it were my bitch having a litter before I agreed to anything. Or maybe I'm being over cautious ?? Not sure as I've never bred a litter nor had an entire male in the show ring before.
Thoughts anyone ?

Most definately! You need to be just as clued up on your breed and lines to evaluate whether a bitch is suitable for mating to your dog! Also the Stud dog owner should be willing to help with the pups that are produced.
My oldest bitches sire is one of my main mentors, as I sought her advice as much as the bitches breeder. My breeder also had a well known Stud Dog and worried about his puppies as much as any she bred herself.
By JaneS (Moderator)
Date 24.01.02 09:50 UTC
I couldn't agree more - it's only in the last few years that we have felt experienced enough to offer a dog at stud & even then we did so reluctantly (people were asking to use our boys) as it is a huge responsibility. You certainly do have to know pedigrees inside out - how else can you advise bitch owners whether your dog will be a suitable match with their bitch if you don't know the possible problems that can crop up in certain lines? We also keep in close contact with breeders who have used our dogs, visiting the pups if possible & passing on enquiries - we also wouldn't hesitate to help rehome a puppy sired by one of our boys, should this be necessary.
It's not the show breeders I have a problem with generally, it's the owners of pet bitches who ring up because they have heard we have 2 stud dogs - sometimes they have done their homework but most have not - they have no interest in pedigrees (some don't even know what their bitch's pedigree is), no interest in health screening tests like eye-testing - they just want a litter of puppies. Sometimes they are willing to be "educated" but many are not so no doubt they go off & find some other stud dog whose owner may not be so picky :-(
Jane
By sierra
Date 24.01.02 09:36 UTC
I fully agree. Unfortunately, when something goes wrong with in a matching of genes, most people, wrongfully, say 'look what so-and-so threw' or 'did you know that so-and-so produced a puppy with ****'. Maintaining a stud dog is an excellent topic for discussion.
By philippa
Date 29.01.02 17:04 UTC
Hi sierra, some more info for you. Irish Wolfhounds, Heart disease, various cancers, gastric torsion, Liver shunt, and a few less serious problems!!!
Australian shepherds, PRA and HD
By sierra
Date 29.01.02 17:52 UTC
Thanks Phillipa....how about giving me a call and we'll have a good natter about it.
By Quinn2
Date 29.01.02 20:30 UTC
:)
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