Absolutely gutted, please no judgement. I’ve just had my dog scanned after Alizin injections 3 weeks ago and she is in whelp, my brother in law let her out when he was babysitting, he just didn’t realise how fast it would happen. I’m so gutted because she only had a litter in March, albeit just 2 pups. Has anyone experienced the injections not working? I’m devastated, my male dog is booked in to be neutered next week

How soon after being mated did she have the Alizin ?

From the NOAH compendium

In bitches confirmed pregnant, a partial abortion was observed in 5% of cases in field trials. A thorough clinical examination is always recommended in order to confirm that the uterus content is fully evacuated. Ideally, the examination should be conducted using ultrasound. This examination should be performed 10 days after treatment and at least 30 days after mating.
In case of partial abortion or no abortion, repeat treatment may be recommended 10 days after treatment, between day 30 and day 45 after mating. Surgery should also be considered.



I couldn’t find anything online, thank you, I will phone my vet again tomorrow. Thank you

Is your male dog the same breed? Are there any potential health issues with letting the litter proceed? Would it be a disaster if the litter went ahead? If it was my girl I'd probably just let the litter go ahead at this point, assuming he was the same breed and had all health tests done. You've tried to do the responsible thing. 

There is a lot of literature around now that suggests it may actually be healthier for bitches to have litters on consecutive seasons and then be spayed 3 months later. Obviously assuming that she has completely recovered condition from the first litter. IIRC it was something about the uterus being more supple (or something like that).

The only option aside from having the litter is a gravid spay if you don't want the litter, of course she would then be spayed so no more litters.

is she a breed that is likely to have issues giving birth?  how far along the pregnancy is she?  can you afford the time off work to raise a litter? can you afford a c-section?

I know someone whos bitch birthed two puppies after Alizin, I believe they were still born and not totally formed properly.

To answer a few questions, yes both of
the same breed, both KC, no problems whelping the 2 earlier this year. We can afford a c section and am able to work from home so no problem there. I’m just devastated for her. Thank you for your replies xx

If this were my situation, and depending what you had planned for your bitch (to take more litters from her, regardless of what's happened), I'd go for a gravid spay.   And I'd not castrate the male because although it would prevent him siring litters, that's all it will stop.   Castrated males can and will still be interested in a bitch in season.   Better would be to get her spayed.  IMO.

If you are concerned about litters from consecutive seasons, I knew of people (not in this country) who had problems getting one of their bitches in whelp but they were finally successful.   As she only had a small litter, they bred her again on her next season when she again conceived, and after that, she was spayed.

As others have suggested, I wouldn't neuter your boy.

I don't like the sound of a gravid spay either, in the 'old days' may people bred their bitch on consecutive seasons with little issues.  Your only problem is how the Alizin has affected the puppies.

I think I would let her have the puppies and take it from there...

Re litters from consecutive seasons - I thought the KC didn't accept registration of a litter taken from a bitch within 12 months?  That may have changed.

Yes they do allow litters from consecutive litters.

I don't think they will accept registration if you're a licensed breeder

Licensed or assured breeders can't register b2b litters

I know of an ABS breeder who did!

I’m sure I read the only reason you could register back to back litters with the KC is if it was an accidental litter although how they would prove it wasn’t in order to refuse I don’t know. Didn’t see anything saying it was different if you are licensed or ABS but doesn’t mean it’s not there

The law does not allow a breeder requiring a licence to breed a second littwr from a bitch in under 12 months.

Oh yes Brainless of course. Although the KC do still allow accidents to be registered if it is back to back

But only for breeders that are not considered commercial by UK legislation.

Ah I see!

Isn’t there Mifepristone (RU486) available in the UK? Around 25 days gestation this can be given I believe

It is not licensed for use on animals

Lots of things that are not licensed for use on animals can still be used if a vet judges them to be medically necessary. Metronidazole wasn't even licensed until very recently...

>Lots of things that are not licensed for use on animals can still be used if a vet judges them to be medically necessary.

The cascade system means that unlicenced products can't be used if there are suitable licenced alternatives; and Alizin is licenced so would have to be the first option.

I would be asking vet experienced in reproduction issues what is safest for the bitch.  which option puts her life at least risk.

>Alizin is licenced so would have to be the first option

Which is why it was tried first... we're not on the first option!

what did you decide to do in the finish?