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Topic Dog Boards / Health / Haemophilia
- By Rubels1968 [gb] Date 29.07.20 15:11 UTC
Can anyone tell me if a bitch's father had haemophilia ..would she also have it?
Thanks
- By Jodi Date 29.07.20 15:31 UTC
Found this

https://vcahospitals.com/know-your-pet/hemophilia-a-b-in-dogs
- By suejaw Date 29.07.20 16:23 UTC
Not necessarily. There is a DNA test for type A and type B if its known in the breeds at Laboklin. Reading it through tbey can be clear, carrier or affected 
If an affected is mated to a clear then the offspring will be carriers if females and the males will be clear.
- By Ann R Smith Date 29.07.20 19:23 UTC
Only if her mother one or two of the gene as the gene is carried on the X chromosome. She will be a carrier however. Female haemophilliacs are exceptionally rare BTW

In breeds in which haemophillia occurs( GSDs , Dobermanns etc)all males should be tested before being bred from & affected dogs should never be used in a breeding program.

The German SV forbids the registration of puppies from affected dogs & as all dogs have to be DNA tested beforw being bred from, the occurance of haemophillia in their dogs is virtually nil.

I cannot understand anyone breeding from an affected dog, even if he was the best dog ever in the breed.
- By Ann R Smith Date 29.07.20 19:31 UTC Edited 29.07.20 19:36 UTC
Reading it through tbey can be clear, carrier or affected


Not correct

All males with the single gene are affected not carriers as the gene is carried only on the X chromosome which males get from their dam. The gene is on the part of the X chromosome that doesn't have match on the Y chromosome(Y chromosomes are shorter than X chromosomed in dogs)

Males can only be normal or affected

Females having 2 copies of the X chromosome & they are the ones that are normal, carrier or affected
- By suejaw Date 29.07.20 20:15 UTC
I've added the bit underneath about how it works with an affected to clear mating as per laboklin testing
- By Rubels1968 [gb] Date 29.07.20 21:44 UTC
Thanks all ..very much indeed. Really informative.
- By Ann R Smith Date 29.07.20 22:10 UTC Edited 29.07.20 22:12 UTC
But males who have the haemophillia gene on the upper part of the X chromosome are haemophilliacs not carriers. A carrier is an animal that is not affected by the mutant gene. Conditions like haemophillia that are carried on their single copy of the X chromosome upper section only have 2 statuses affected or normal in males, hence the reason for not using them to breed from(apart from the danger of the sustaining any injury)
- By Wait Ok Date 31.07.20 07:57 UTC Edited 31.07.20 07:59 UTC
Laboklin; Haemophilia A explained.

https://www.laboklin.co.uk/laboklin/showGeneticTest.jsp?testID=8222D&testID=8222D

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- By Wait Ok Date 31.07.20 07:59 UTC
Laboklin; Haemophilia B explained.

https://www.laboklin.co.uk/laboklin/showGeneticTest.jsp?testID=8221D&testID=8221D

.
- By CaroleC [gb] Date 31.07.20 11:31 UTC
There is also Factor VII deficiency, which is a less serious form of haemophilia. Breeds which can be affected are the Airedale, Giant Schnauzer, Klee Kai, Beagle, Deerhound, Finnish Hound and the Welsh Springer Spaniel. The dna test for Factor VII is included in the KC bundle for the Beagle.
Topic Dog Boards / Health / Haemophilia

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