
I would not split them up but have them all with Mum and latch smallest pups on most often, as the bigger ones drop off. Most bitches have 10 nipples, and with a big litter soon learn how to lie so that they can feed.
Bitches even in my medium (20kg) breed have managed to feed large litter of 12 - 14 with no more than plenty of food for Mum, and an attentive breeder making sure they all got fair dibs.
Separating pups for any time from Mum would upset my bitches too much and would possibly stress them so that lactation was affected.