https://vcahospitals.com/know-your-pet/puppy-fading-puppy-syndrome-in-dogsHere is info about Fading Puppy Syndrome - there are loads of websites with information too
Is the puppy noisy - FPS normally presents with the puppies making a noise like a seagull. Very distressing to everybody. Many times a 'Sectioned puppy will lose a bit from birth weight, but quickly make it back up again as they nurse ... and after all, a singleton has the whole milk bar to get at. Mum could have had more puppies, but whatever caused them to be lost could have affected this puppy too - she was just strong enough constitutionally, to make it into the world. Even at this age, you could try a little natural yogurt on the tongue - just a tiny amount. This is a probiotic so could help. She will need to be kept extra warm, not having any siblings to snuggle with and another thing that occurs to me - mum may run into mastitis if she starts producing a lot of milk, and it's not being drawn off sufficiently, with just one puppy - she needs to be rotated amongst the teats.
You can really only keep a close eye on her (nice to have a female singleton puppy - all too often they are males although the one we had, was female) and hope for the best. Good luck.