I had a babyjogger performance, which has 20 inch bike style wheels. I used it as intended (to run, pushing kids) for about 8 years. It lasted through 3 children and in fact outlasted my knees and went on to another family for use.
My 3.5yo has autism, including sometimes involuntary refusal to walk, and we have a McLaren major elite pram for him (cross between a pram and a wheelchair, can be used from 3-7 years). I am currently pushing my 9wo standard poodle pup in it at times (vax not complete yet).
You get funny looks, is all I would say.