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Topic Dog Boards / Health / Cocker spaniel question re health tests
- By fink1 [gb] Date 10.03.16 17:22 UTC Edited 10.03.16 17:25 UTC
Hi,
could anyone clarify this for me re health tests for my  Girl I want to make sure i understand ..as have got my head round the PRA & FN that important for this breed
i have had her tested for PRA & fN  which she is Clear

Her great grand parent on mothers side is
Eye test unaffected is that the yearly bva one ?
eye test clear gb BVA Gpra/Cpra  ?
& Gonia Unaffected (is this glaucoma)
so is she hereditary clear on these ..& would her pups be?    even though i would still use a health tested stud,but say he was only pra clear for example
By the way No she has not been bred already Just gaining knowledge

Thank you
- By Wait Ok Date 10.03.16 21:10 UTC Edited 10.03.16 21:23 UTC
The Optigen prcd PRA is a DNA-based test that helps you avoid one form of (PRA).

PRA refers to a group of deasises that cause the retina of the eye to degenerate slowly over time.

The result is declining vision and eventual blindness, "prcd" stands for "progressive rod-cone degeneration" which is the type of PRA known in several breeds.
As mentioned previously PRA  refers to a group of deasises of which the "prcd" is only one.    You should have official certificates for each DNA test performed.
FN; Dogs with FN typically develop chronic renal failure between 6 months and 2 years.
The BVA eye test is only a "clinical" examination and the whole eye is examined for many more indications of deasise, this is only what the BVA examiner can detect on the day of the examination  (it is not the same as licensed DNA testing). The Gonio (Glaucoma) test performed by a BVA vet is however a one off and covers the Cocker Spaniel for life.
To get an official BVA certificate this test must be performed by a professional/licensed BVA vet.

A BVA clear clinical tested dog and a clear DNA tested dog can NOT produce HERIDITARY CLEAR PUPPIES.

Both parents; the father and the mother must be DNA clear for the puppies to be "hereditary clear" this is the same for both FN and prcd PRA.

Both of your girls immediate parents must be DNA tested clear for this to become hereditary clear! and the same for the puppies.

From what you are saying your girl is NOT Hereditary Clear!

Phew!   I hope that makes sense for you.
- By Brainless [gb] Date 10.03.16 21:55 UTC Upvotes 1

> From what you are saying your girl is NOT Hereditary Clear!<br />


but if you have had her tested and she came back clear for DNA tests for both then what went before is immaterial, she is GENETICALLY CLEAR.

If mated to a DNA tested clear dog her puppies will be GENETICALLY CLEAR and listed as HEREDITARY CLEAR.

If you use a DNA tested Carrier dog then the pups used for breeding will need DNA testing themselves to determine their genetic status, but they will be UNAFFECTED, whether they are clear or carrier doesn't'; matter unless they are bred from..
- By rabid [je] Date 10.03.16 22:03 UTC
The annual BVA eye test is just a snap-shot of the dog's eyes at the time the test is done.  Conditions can arise after the eye test, which weren't able to be detected, previously.  That is why the BVA eye test needs to be repeated annually for breeding stock (or at least, for bitches, a test needs to have been done within the year they are bred, if you're not going to do annual testing).

The DNA tests do more than just a 'snap shot' - they can determine if the dog will ever, even years in the future, develop a condition.  That's why they only need to be done once.

However, the DNA tests can't check the eye for every condition that exists - they look for very specific strains of conditions.  So that's why dogs also need the annual eye test, to check for those other conditions not covered by the DNA test...
- By Jan bending Date 11.03.16 07:35 UTC
Your girl should also be DNA tested for the condition Acral Mutilation Syndrome (AMS)

This is a most distressing condition in which the  affected dog/puppy  persistently chews at its extremities causing severe damage /mutilation. The condition is a form of sensory neuropathy and has  an autosomal recessive mode of inheritance. The DNA test identifies carriers, affected as well as those clear of the condition. I wrote a bit about this in 2011 and the DNA test was developed a couple of years ago. Carriers were identified across the breed and responsible breeders have taken steps to control the condition. AMS  is also present in Pointers, English Springers and Minature Schnauzers. A very rare form has been described in Border Collies. When you are deciding on a stud dog for your girl, please ensure that he has tested clear  for AMS
- By fink1 [gb] Date 11.03.16 14:04 UTC
Hi,
i'm a little confused lol
Have been looking at health tests for her ..
(I had her tested for the PRA & FN which is Clear  so thsi is a good start

Its the Gonia one that i'm a little confused about as think that this is the Glaucoma Test that you have do do at specialist vets
, Think also the annual eye test Can't even be done at our vets either
I don't mind getting it done (when i find a vet) but if she is clear through the grand parents or something then she is clear right ,if that makes sense,although don't have a certificate,but is shown on a forum that that dog is Tested & some of the others have been tested for PRA
Seems there are different PRA conditions too CPRA & GPRA   so PRcd PRA is this the Gpra or another one ermm lol

Thanks all for your responses so far

( Have seen the test for Ams Jan i can send off for the kit to do that .. )
Most stud ads i've seen so far  are tested for PRA & FN mainly
Not many Glaucoma tested Ams or anything else & they seem to be long time breeders too
Thanks again all
- By Jan bending Date 11.03.16 15:14 UTC Upvotes 1
Hello Fink1

      Re. eye testing . Your own vet is probably not qualified to do this.  You need to take your girl to a eye testing clinic where a specialist veterinary ophthalmologist, also called panelist, will do the eye examination and issue a certificate accredited by the BVA.  There are only  30 or so panelists in the UK . Some veterinary practices run a monthly clinic with a panelist , and many dog shows have a clinic running on the day. We have one coming up next week in East Sussex.  Whereabouts do you live ?
Re. Glaucoma testing. Glaucoma is a terrible eye disease in dogs, far more painful than in humans . Many breeds have inheritable forms of Primary Glaucoma. I am mainly familiar with narrow angle glaucoma.
Gonioscopy is the test that looks for abnormalities in the eye that could lead to glaucoma. These abnormalities are termed goniodysgenesis  with narrowing of the drainage canals in the eye structure and thickening of one of the supporting ligaments ( pectinate) The narrowing of the drainage canals leads to a build up of  fluid and pressure in the eye and subsequent damage to the optic nerve and retina. Not all dogs with goniodysgenesis go on to develop glaucoma but in some breeds it most certainly has and equally certainly has been proven inheritable.
Glaucoma testing is done to measure the pressure within the eye using a tonometer.  I'm no expert and I'm sure other forum members could give you more breed specific info.
If your girl requires gonioscopy -and this can be done at the time of her first eye test - just make sure the assistants do not put in the eye drops ( midriatic) normally used to dilate the pupil in preparation for the normal testing ( PRA/CEA/ MRD..whatever)  The gonioscopy must be done first. The vet will put some local anaesthetic drops in , do the gonioscopy and then proceed to do the regular eye test  having put the midriatic drops in.
Gonioscopy used only to be done once but I understand that some research advocates more regular testing.  After all this, you will still need to have your girl tested annually and have up to date certification of this. Because most breeds do not have a DNA test for the type of glaucoma prevalent, it cannot be a taken that because grandparents etc were clear, your girl must be. The mode of inheritance may not be known.
Hope this helps
- By Dolph [gb] Date 16.03.16 08:44 UTC
IF your cocker is working strain she will need to be DNA tested for AMS.
http://www.antagene.com/en
Topic Dog Boards / Health / Cocker spaniel question re health tests

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