
The lymph glands will react if the dog is fighting infection. Having enlarged glands doesn't necessarily mean Lymphoma. Sadly I felt a large mass in one of our hounds. Instead of doing a fine needle aspiration from there, my then vet went into his rear glands and sadly it came back with the last result I wanted to have to face. He was going on 12 at the time, so after much discussion as you can imagine, we elected not to treat him at all. He was actually perfectly well at the time. And stayed that way for 6 months (to the point I started thinking the results were wrong). At the end, he suddenly crashed. I called him for his second meal of the day (unusual for starters as he'd normally have been there, front row centre) and he still didn't come so I went to find him - collapsed on the living room floor. Called my husband home with the car to get him to our vet who gave him an injection to hopefully kick start him again - it didn't. So the next morning we had to take him back to be pts.
If you are asking what to do - you can only be advised by your vet about what's now going on. Just to say I didn't want to put my old boy through chemo. even if they do tolerate this usually, far more than we do. it would still mean him going to and from the vet - with no real long-term prognosis. So we gave him what time he had left, and then helped him. My neighbour put an oldie through chemo, and said never again.