
I'm so sorry for your friend. I went through similar with my girl in December so know pretty well how she must be feeling.
C section and nearly lost the mum on the table - 3 surviving pups. She was very poorly for a while.
Puppies got diarrhea, first coming down as a day old, she was just constantly leaking out of her bum :(.
She had antibiotic injection&I was supplementing her as she was too weak to suckle.
We lost her after 14 hours fight, I thought maybe she had something wrong with her(organ not working properly)...
Sadly next one came down with it very soon after losing the first so I knew it was probably some kind of bug we were fighting against.
Of course I was going to fight to save her so after thinking very hard what to do off to the vets we went again.
Antibiotic injection and liquid under the skin.
The vet basically told me I'm going to lose her too and was not going to give me any more antibiotics to continue after the injection wears out :(...
But I fought my corner and said I want some, I'm paying for them so should be given some regardless of the fact they think the puppy will just die.
I also got some liquid to put under her skin for when she gets de-hydrated.
By this point I must have been looking like right mess as I had been up for nearly 2 days, was very worried of my girl and the pups.
I think to shut me up and make me happy for little while they gave me what I asked for.
This time the puppy was little stronger and I decided to keep putting her on to mum every 45-60 minutes for as long as she was strong enough to suckle even little(and keep an eye on her hydration and rehydrate when she got dehydrated).
We had about 4 hours where she got very weak and stopped suckling & I thought I will loose her too but just like a miracle she picked up and started suckling again after that (I kept her hydrated through).
Of course we did not know how long the diarrhea will last or if it will ever pass.
The bug lasted for little over 24 hours and she started to not constantly leak but actually had periods when she stayed dry for a little while.
Then slowly over few days the poop firmed and got back to the normal puppy poop texture(except it was bright green due to the antibiotics).
Just when I thought we were out of the woods, the last puppy started with it!
It is such a difficult situation and trying to decide what is the best thing to do especially when you are knackered and different people advise different things Keep the pups on mum/take them off mum, separate the sick puppy from the rest/keep them all together, give milk supplement, give lifeaid, to give antibiotics or not...)
Is it bacterial infection, virus, mums milk, should tests be carried out on poop, milk -will the results come in time to do anything about it?
After loosing the first puppy so quickly I really thought I'm fighting a battle I will loose but the other two pulled through!
I hope rest of your friends puppies stay healthy but if they do come down with it, try supporting your friend through it.
I was sat in the phone with different friends through it all and those few encouraging words and somebody just listening really helped me to cope in the moments I felt the lowest!
I hope your friend will manage to find a vet that knows what they are talking about as that could make a big difference in survival of the pups if they come down with something.