Advert in our local weekly paper for GSD pups NO I'm not looking for one, 'orrible 'erbert is quite enough

GERMAN SHEPPARD PUPPIES Superb pedigree. Hip scored parents. Dad haemophilia clear. KCGC GOLD. Breed Class 1 .
Mum CDRM clear. PD clear. Vaccinated,  Insured. 

No mention of KC Reg or elbow scores, but have I missed something new about CDRM testing, or does a BYB have a good imagination :-(
also what is PD in relation to GSDs.

Chris

I expect with all that the KC reg goes without saying, I must admit I tend to think that it is, and have to remember to mention ti if I ever advertise outside breed publications.

ALso on another site.

To pet homes please.   This is what it states on it and that parents are KC reg..

first and only litter, we are not breeders and wanted a puppy of this calibre ourselves - ummm, maybe mum has endorsements?

Maybe worth a call to find out pedigrees? Check on KC website and then maybe contact breeder of the bitch to find out?

>first and only litter, we are not breeders

Aaaarrrrgh! *bangs head on wall* Yes, they are breeders! You only have to have one child to be a parent, and your bitch only has to have a single puppy for you to be a breeder!!!

*goes to lie down*

> Yes, they are breeders!  - That was you speaking out loud in reply to their statement right?

Indeed.. Oh how i'd love for that site amongst others to be closed down.. Idiots, total idiots..

There is a Cdrm test (Dna) available now for GSDs.  It is a relatively new test and I have had my bitch tested due to her having a litter at the end of the year.  I am surprised more breeders don't know about this test and take advantage of it.  It is such a common disease and god awful as I am sure most people are aware. My bitch is also hip scored, elbow scored, eye tested and the dog I am using is hip scored, elbow scored, hameo tested.

Oops, that wasn't supposed to sound like an advert!  The lab I used for the cdrm test is called LABOKLIN.  If you google them you will find the test.  It costs around £80, small amount of money for peace of mind and as a bonus my girl came back clear!  I have heard of two other test results from people I know and one dog tested as a carrier, one as affected.

I've been having a search about and can't find anything about PD in GSD'S, well not from search engines.

Photoreceptor Dysplasia is what does come up, but this seems to be something for another breed.

Pituitary Dependent is something else relating to Cushings, can this be tested for and is it a problem in GSD'S?

Not sure what the PD is all about???

Oh I know what they mean! Its Pituatry Dwarfism.  It is a problem is some lines of GSD, not very common though unlike CDRM. PD to me always means the working trials qualification!

Think I've mispelt the pituitary!

I did not know that CDRM is hereditary?  Is this correct?  Reason I ask is my akita has been diagnosed with this recently and he has sired 2 litters when he was younger.

Could PD stand for Pituitary Dwarfism, which I know does occur in GSD's and leads to health issues and short lifespan???

Hi Brainless, this was my thought too, see my post a couple earlier.

CDRM is thought to have a hereditary component yes.

I hadn't read down to the bottom when I posted. :)

Thanks everyone for all the info, it was the mention of the cdrm test that got me as when I lost my first shepherd Zigi to this about 12 yrs ago the experts were still undecided if it was genetic or environment or what. That is really good news that they can test now as cdrm is such a dreadful thing. My boy had 8 months of getting worse till we made the big decision but the horrible thing was right at the end the brain was still 'up and at em' but the back end just wouldn't respond..........sat here 'filling up' thinking about it even after all this time.
Chris

Is this the DM test that's available for all breeds developed in the US?  Because if it is, there is some doubt on the validity of it for GSD.  GSD DM is still being researched.  This is last update I came across - February 2010.

Following a literature search for diseases in other species with clinical and pathological similarities to CDRM, a working hypothesis was established: CDRM is caused by a CAG trinucleotide repeat expansion in an unknown gene. A number of molecular biological techniques were employed to test this theory, including the Repeat Expansion Detection (RED) technique. This work is still in progress but there is some evidence, still inconclusive, that CDRM may be the result of a trinucleotide repeat expansion. Undoubtedly, CDRM has a complex aetiology which probably involves several different factors but most authors agree there is almost certainly a genetic factor due to the very high incidence of the disease in one breed. [The results from the Glasgow experiments provided some evidence that CDRM is principally genetic, and specifically of an "expansion" as noted, in the CAG nucleotide sequence on a gene that yet has to be found or marked.

http://www.fredlanting.org/2010/02/the-new-knowledge-of-dm-%E2%80%9Cgsd-myelopathy%E2%80%9D/

If you go to the GSD Breed Council site you can contact Sheila who will put you in touch with the man who organises this testing and can give you more info on it.