The girl that i am mating next year her grandfather is in the predigree 3 generations back  of the stud dog will it be alright

What else in in between? Do you know anything about the other dogs listed there?

This mating on paper is fine,but you really need to know the possitive and negative traits that the grand father has in his genetic make up.If there was something good that you were looking for in this breeding eg he has good tail carriage or something you are looking for in improving your line,then great.If there is something undesirable that may come out in this mating then obviously caution should be used.
My latest pup has the same grandfather on both sides but his G-dad and generatons behind him have good bone.Something which can lack in my breed.Hopefully my girlie will take after him.Hope this makes sense.

Yes MsTemeraire i do know the dogs inbetween. Yes cornishmals i am looking to inproving tail carriage at the moment i do not seem to be able to get straight tails. The grandfather comes from a very good line. Which i know of & seen & was very inpressed by.