
In theory you can induce a fertile season in a "normal" bitch using a drug called cabergoline. It is relatively expensive and typically takes 13 days or so to induce signs pro -oestrus, blood testing would need to be undertaken to ensure hormone levels had increased adequately to produce full ovulation as you can have signs of season without the bitch actually producing eggs. In bitches who responded sucessfully to the drug studies have shown that conception rates after inducing seasons with this drug are approx 77%.
If you want to consider breeding from this bitch I would seek a referral to a canine reproduction expert who will be able to advise on investigations of the cause of her prolonged anoestus as a first stage - as Brainless says even if you can get this girl to have a season, and can get her in whelp, you may just be store up problems in the next generation. If all early investigations seem ok then you could move onto breed specific health testing and if still not in season after all that could perhaps try inducing a season with support from the repro expert.
This will certainly not be a quick process, it will be very costly and there can be no certainty of getting pups. Probably only worth the effort if the lines are considered too valuable to loose.
K