I'm sure you've seen some of these before but I think there are a few new ones.  Feel free to add your own creative additions.  I guess I'll have to find the Newfie/Basset cross since that is my profession.

Pointer + Setter =
Poinsetter, a traditional Christmas pet

Kerry Blue Terrier + Skye Terrier =
Blue Skye, a dog for visionaries

Great Pyrenees + Dachshund =
Pyradachs, a puzzling breed

Pekingnese + Lhasa Apso =
Peekasso, an abstract dog

Irish Water Spaniel + English Springer Spaniel =
Irish Springer, a dog fresh and clean as a whistle

Labrador Retriever + Curly Coated Retriever =
Lab Coat Retriever, the choice of research scientists

Newfoundland + Basset Hound =
Newfound Asset Hound, a dog for financial advisors

Terrier + Bulldog =
Terribull, a dog prone to awful mistakes

Bloodhound + Labrador =
Blabador, a dog that barks incessantly

Malamute + Pointer =
Moot Point, owned by....oh, well, it doesn't matter anyway

Collie + Malamute =
Commute, a dog that travels to work

Deerhound + Terrier =
Derriere, a dog that's true to the end

Cocker Spaniel + Rottweiller =
Cockrot, the perfect puppy for that philandering ex-husband

Bull Terrier + Shitzu =
Bullshitz, a gregarious but unreliable breed

Ahh- my swedish lapphund must have been a Blabador!

a few more

Collie + Lhasa Apso = Collapso, a dog that folds up for easy transport

Retriever + Irish Setter =  Resetter, a dog that can set your vcr for you

rottweiler x Beagle = Reagle, dog that thinks he's better than you

ooh, very good.  I think these are just great and I envy those with the imagination to come up with them.

same cross- different name
rottweiler X cocker spaniel= rottencock!

In our local paper someone is advertising
Bulldozers Bull mastif/ Dobermann

>Bulldozers

Yes, I've seen these advertised online! Bulldozers - not kidding! Can you imagine

So that would be - a dog for those in the construction business?

Maybe a Cockalier for the workmen on building sites, because of the leering??