Hi my new 6 week old maltiez shitzu,wont quit crying,at night any suggestions,when i pick him up he just starts biting me and chewing at my cloths its driving me crazy what do i do,

He's homesick and missing his mum and his littermates. You have to become them, so keep your tiny baby (he's too young really to have left his mum anyway) company. As for the biting and chewing, that's 100% normal - it's what puppies do. Read this which will help you teach him gentleness, though if he'd been with the rest of his litter for longer some of this training would have been done by them.

He is very, very young to have left his mum - most toys stay with mum & breeder until they are 12 weeks old :(