
Have jsut got out a pack of Puppy & Kitten stronghold and read the leaflet - it does not give a minimum weight it is safe for, just less than 2.5 kg, and not under 6 weeks, so reading this it sounds like your firend can use it OK. However I would be very reluctant to use on such tiny pups, much prefer using a liquid wormer which can be dispenses accurately according to indiividual pups weight, and frontline spray if flee control is required.
I have a large Toy breed (contradiction in terms :) ) and only use Stronghold from 12 weeks old, the pups are suaully around 2.5 kg by then.