
Yes it is most likely to be the frontline, dogs can and do get adverse reactions to flea treatments, wormers and boosters. Frontline is very strong and some dogs have actually had their skin burnt in the area it is applied. A dog I had used to go very strange, rolling over and then used to look at the wall in a daze for a couple of hours after using flea treatments. Unfortunatley I used to believe the vet when he said it was unlikely to be the flea treatment, and I continued to administer it every 3 months. Complete fool!
You can protect your dog against fleas by feeding them garlic each day fresh or capsules and also by adding vit b (like brewers yeast) to their diet. It is effective and safe.
It might be worth giving your dog some Thuja (homeopathic remedy) for a few days which will help with adverse reactions.